脳卒中に関する基礎的研究 (第3報)

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タイトル別名
  • Basic Study on Cerebral Apoplexy (Report 3)
  • ガンテイ ショケン ト モウマク ドウミャク ノ ビョウリ ソシキガクテキ ショケン ナラビニ ノウ ジコ ト ノ カンケイ ニ ツイテ
  • Relationship between Clinical Findings of Eyeground, Histopathology of Retinal Arteries, and Cerebral Apoplexy
  • 眼底所見と網膜動脈の病理組織学的所見ならびに脳事故との関係について

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Correlation between collagenous fibrosis in the media of the retinal arteries and cerebral apoplexy was presented in the second report of this series. If the correlations between clinical findings of the eyeground and pathological findings of the retinal arteries are, therefore, confirmed, the occurence of the cerebral apoplexy may be predicted. In the present study, the clinical findings of the eyeground were correlated with the histopathlogical findings of the retinal arteries and then with cerebral apoplexy.<br>One hundred and four cases, which were fundoscopically examined the eyeground prior to death, were selected among materials used in previous two papers, and were used in the present study.<br>The narrowing, an increase in reflex, and the irregularity in caliber of the retinal artery, arteriovenous crossing, silver-wire artery, white thread artery, bleeding and white spot in the retina, and the slightly modified classifications by Keith-Wagener as well as Sheie were fundoscopically observed and were used in this investigation.<br>The results were as follows:<br>The narrowing of the retinal arteries and the retinal bleeding likely correlated with the medial hypertrophy of the retinal arteries.<br>An increase in reflex and narrowing of the retinal arteries, and arterio-venous crossing seemed to correlate with the medial collagenous fibrosis of the retinal arteries.<br>Incidences of cerebral apoplexy in each group of II a, II b, III of Keith-Wagener's classification, and II, III, and especially in grade IV of Scheie's classification for sclerois, and I, II, and III of Scheie's classification for hypertension were higher than those in other groups.<br>Fundoscopic findings which correlated with cerebral apoplexy were likely narrowing, increased reflex and irregularity in caliber of the retinal arteries, and arterio-venous crossing.<br>There was only a little correlation between the retinal bleeding and cerebral apoplexy. Therefore, the retinal bleeding is not so useful in prediction of cerebral apoplexy.

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