Effect of deep inspiration of maximum expiratory flow (Vmax) depends on basal bronchomotor tone in young healthy females.
-
- Fujimura Masaki
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Nomura Masaharu
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Sakamoto Sayuri
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Kamio Yumie
- Central Clinical Laboraoty, Kanazawa University Hospital
-
- Shibata Kazuhiko
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Ogawa Haruhiko
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Nishi Kouichi
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
-
- Matsuda Tamotsu
- The Third Department of Internal Medicine, Kanazawa University School of Medicine
Bibliographic Information
- Other Title
-
- 若年健康女性におけるｂａｓａｌ ｂｒｏｎｃｈｏｍｏｔｏｒ ｔｏｎｅと深吸気のｍａｘｉｍｕｍ ｅｘｐｉｒａｔｏｒｙ ｆｌｏｗ （Ｖｍａｘ）増加効果の関係
Search this article
Abstract
The relationship between the effect of deep inspiration on Vmax and basal bronchomotor tone was studied by partial and maximum expiratory flow-volume curve in 16 young healthy females (20-21 years old).<br>Effect of deep inspiration on Vmax (DI index; (PEF25-MEF25)/PEF25) significantly related to percent increase in PEF25 not only by inhalation of ipratropium bromide (r=-0.81, p<0.0002) but also by inhalation of salbutamol (r=-0.62, p<0.01). Furthermore, day to day variation of DI index significantly related to day to day variation of PEF25 (r=0.68, p<0.005) but not to that of MEF25.<br>These findings suggest that the bronchodilating effect of deep inspiration in young healthy females may depend on intensity of basal bronchomotor tone caused by tonic vagal nerve activity.
Journal
-
- The Japanese journal of thoracic diseases
-
The Japanese journal of thoracic diseases 28 (1), 105-112, 1990
The Japanese Respiratory Society
