Delayed type hemolytic transfusion reaction with non-detectable irregular antibodies.
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- Matsuo Yuko
- Blood Transfusion Service, Kumamoto University Hospital
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- Nishimura Yoko
- Blood Transfusion Service, Kumamoto University Hospital
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- Yamaguchi Kazunari
- Blood Transfusion Service, Kumamoto University Hospital
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- Takatsuki Kiyoshi
- Blood Transfusion Service, Kumamoto University Hospital
Bibliographic Information
- Other Title
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- 不規則抗体が検出されない溶血性輸血副作用をRh因子適合血により予防しえた1症例
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Abstract
A 52 years old woman with ruptured esophageal varix, who had hemolytic transfusion reaction without any detectable irregular antibodies in her serum, was reported. She had history of twice blood transfusions on each caesarean operation in 1979 and 1980.<br>She has received 10 units of fresh whole blood from 16 to 18 May in 1988. Ten days after blood transfusions, she noticed hemoglobinuria. Laboratory tests showed increase in LDH and indirect bilirubin levels with decreased haptoglobin level.<br>The irregular antibodies were weakly detected in her serum by low ionic strength polybren method on the Autoanalyzer, but not by saline, albumin, bromelin and indirect antiglobulin method. Specificity of the antibodies were anable to be identified, and direct antiglobulin test wa negative. The blood groups of the patient were A1, ccDee. She received blood with Rh phenotype of ccdee. Ever since, she has been saved from occurrences of any hemolytic reactions. Thus delayed hemolytic transfusion reaction by anti-E+C was mostly suspected, though irregular antibodies could not be detected in her serum in March, 1989.
Journal
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- Journal of the Japan Society of Blood Transfusion
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Journal of the Japan Society of Blood Transfusion 36 (1), 73-76, 1990
The Japan Society of Transfusion Medicine and Cell Therapy
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Details 詳細情報について
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- CRID
- 1390001204909499392
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- NII Article ID
- 130003706742
- 80005278705
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- ISSN
- 18838383
- 05461448
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed