Metabolism of drugs. XXVI. Metabolic fate of p-hydroxybenzoic acid and its derivatives in rabbits

• 塚元 久雄

• 寺田 精介

書誌事項

タイトル別名

• Metabolism of Drugs. XXVI. Metabolic Fate of p-Hydroxybenzoic Acid and its Derivatives in Rabbit. (2).
• Metabolic fate of p-hydroxybenzoic acid and its derivatives in rabbit (2)

抄録

The ether-type glucuronide of p-hydroxybenzoic acid was isolated from the urine of rabbits receiving methyl p-hydroxybenzoate and its structure was established as p-carboxyphenyl-β-D-glucopyranosiduronic acid. Three main metabolites, p-hydroxybenzoic acid, p-hydroxyhippuric acid, and the ether-type glucuronide, were identified in the urine, and the ester-type glucuronide and p-carboxyphenyl sulfate were proved as minor metabolites by means of paper chromatography.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 10 (2), 86-90, 1962

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390282679151191040
• NII論文ID: 110003618808
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.10.86
• COI: 1:CAS:528:DyaF38XksFamtr4%3D
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/10/2/10_2_86/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1963047298
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可