Studies on Acetylenic Compounds. XX. Carbon-Carbon Alkylation with Acetylenic Mannich Base.

• 岩井 一成

• 平岡 哲夫

抄録

It was found that methyl iodide of acetylenic Mannich base reacted with active methylene compounds to form alkylated acetylenic compounds with a loss of tertiary amine. Various acetylenic compounds may be prepared by this method. It seems likely that such alkylation reactions proceed mainly by S_N-1 mechanism in alcohol and mainly by S_N-2 mechanism in dibutyl ether.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 10 (2), 81-86, 1962

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173995648
• NII論文ID: 110003618807
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.10.81
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/10/2/10_2_81/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1963047344
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可