Benzoisogranatanine derivatives,1

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  • Benzoisogranatanine Derivatives. I. Synthesis of 2'-Hydroxy-5-alkyl-6, 7-benzoisogranatanines.

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Cyclization of 3-(m-methoxyphenyl)-3-methyl (or ethyl) piperidine followed by hydro lysis gave 2'-hydroxy-5-methyl-6, 7-benzoisogranatanine and 5-ethyl analog. The two and intermediate compounds were tested for analgesic activity.

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