Synthesis of 5-Substituted Pyrimidine Nucleosides

• 今井 欣一

• 本庄 美喜男

抄録

Uridine-5-carboxaldehyde (I), uridien-5-carboxylic acid (II), and 1-(β-D-ribofuranosyluronic acid) uracil-5-carboxaldehyde (III) were isolated and characterized form the reaction products obtained after catalytic oxidation of uridine-5-methanol (IV). Five aldehyde hydrazone derivatives of I and III were synthesized. Catalytic oxidation of several pyrimidine nucleosides gave the corresponding uronic acid derivatives. The ease of the oxidation of these compounds was found different, depending upon the base moieties.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 13 (1), 7-16, 1965

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204171721728
• NII論文ID: 110003619449
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.13.7
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 5864288
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/13/1/13_1_7/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1966024682
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可