Steroid series.-18-Acid-catalysed rearrangement product of 3α,5α-cyclo-6,19-dioxosteroid and its conversion to 19-nor-A-homotestosterone

• 林 了三

書誌事項

タイトル別名

• Steroid Series. XVIII. Acid-Catalysed Rearrangement Product of 3α, 5α-Cyclo-6, 19-dioxosteroid and its Conversion to 19-Nor-A-homotestosterone
• Steroid series. 18 Acid-catalysed rearrangement product of 3 アルファ , 5 アルファ-cyclo-6 , 19-dioxosteroid and its conversion to 19-nor-A-homotestosterone

抄録

Treatment of 3α, 5α-cyclo-6, 19-dioxosteroid (II) in a boiling mixture of diluted sulfuric and acetic acids afforded 1β, 4β-oxido-6-oxo-Δ^{5 (10)}-A-homo-19-norsteroid (III), together with a small amount of 3β-acetoxy-6, 19-dioxosteroid (IV), the latter compound, under the same reaction conditions, being converted to the former. The structure of the rearrangement product (III) was discussed. A-homo-19-nortestosterone (XXV) was synthesized from 1β, 4β-oxido-17β-hydroxy-A-homo-19-norandrost-5 (10)-en-6-one acetate (III : R=[chemical formula]).

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 15 (1), 38-50, 1967

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173867776
• NII論文ID: 110003620000
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.15.38
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 8508831
• PubMed: 6040976
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8508831
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/15/1/15_1_38/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1968007918
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可