Studies on Pyrimidine Derivatives and Related Compounds. LX. Synthesis of Hydroxymethylthiamine

• 高見沢 映

• 松本 佐市

• 酒井 昇二

抄録

Hydroxymethylthiamine, phosphate free "active formaldehyde, " was synthesized by the acid treatment of 2-phenyloxalylthiamine-O, O'-diacetate or 2-α-furyloxalylthiamine-O, O'-diacetate, and on alkaline treatment it was converted into a dimeric 1, 4-oxazine derivative (X) involving a ring expansion and auto-oxidation.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 17 (2), 343-347, 1969

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173241472
• NII論文ID: 110003620887
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.17.343
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 5782964
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/17/2/17_2_343/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1970056906
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可