Biochemical Studies on Glucuronides. IV. Cleavage of p-Nitrophenyl Glucuronide by Ultraviolet Light Irradiation at Alkaline Medium

• 山根 靖弘

• 宮崎 元一

• 坂井 和男

• 安食 親孝

• / 吉元 和子

• YOSHIMOTO KAZUKO

抄録

Ultraviolet light irradiation was applied to the study of nonenzymatic dissociation of p-nitrophenyl glucuronide (PNG) at low temperature in acidic, neutral and alkaline conditions. The cleavage of PNG was negligible at acidic or neutral medium, but it was almost quantitative and the production of p-nitrophenol (PN) was over 90% at alkaline condition. Nevertheless, the recovery of sugar moiety of PNG was very low, and glucuronic and glucaric acids were formed only 5-8%, and under 1%, respectively.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 17 (6), 1183-1187, 1969

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173569280
• NII論文ID: 110003620993
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.17.1183
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/17/6/17_6_1183/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1970104559
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可