Studies on Seven-membered Ring Compounds. XXXV. Ring Closure of γ-Cycloheptatrienyl-substituted α, β-Unsaturated Carbonyl Compounds to Benzocycloheptene Derivatives

• 渡辺 泰一郎

• 川本 勲

• 相馬 信夫

抄録

Ring closure reactions of γ-cycloheptatrienyl-substituted α, β-unsaturated carbonyl compounds by acid were examined. Treatment of 2-methyl-4- (2, 4, 6-cycloheptatrien-4-yl) -2-pentenal (II) with hydrobromic acid at room temperature in acetic acid afforded 1, 3-dimethyl- (III) and 2, 4-dimethyl-5H-benzocycloheptene (IV) accompanied by the production of 1, 3, 8-trimethylnaphthalene (V). On the ring closure of 5- (2, 4, 6-cycloheptatrien-4-yl) -3-hexen-2-one (VIII) by a similar procedure, 1, 4-dimethyl-5H-benzocycloheptene (IX), 1, 4, 5-trimethylnaphthalene (X), and 1, 4, 6-trimethylnaphthalene (XI) were isolated.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 18 (10), 2087-2093, 1970

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390282679149329408
• NII論文ID: 110003632227
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.18.2087
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/18/10/18_10_2087/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1971087112
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可