N→N Alkyl and Glycosyl Migrations of Purines and Pyrimidines. I. A New Migration of 3-Alkyl-N<SUP>6</SUP>-acyladenine

• 清水 文治

• 宮木 美知子

抄録

Benzyl, allyl and 3-methyl-2-butenyl groups were found to migrate from N-3 to N-9 or N-7 position of the N⁶-acyladenines. On heating in the presence of hydrogen halide, 3-benzyl-N⁶-acyladenines underwent intermolecular benzyl migration giving rise to 9-benzyl derivatives and a small amounts of the 7-benzyl isomers. 3-Methyl-2-butenyl group in N⁶-acyltriacanthine migrated under similar conditions to afford the 9-(3-methyl-2-butenyl) derivatives, whereas mercuric halide or cyanide caused intramolecular rearrangement to give the 9-(1, 1-dimethyl-2-propenyl) isomers.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 18 (3), 570-580, 1970

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390282679145933952
• NII論文ID: 110003632332
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.18.570
• COI: 1:CAS:528:DyaE3cXktlGgsbw%3D
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/18/3/18_3_570/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1971047412
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可