Biological-Active Triterpenes of Alismatis Rhizoma. I. Isolation of the Alisols

• MURATA TADAKAZU

• IMAI YOSHIO

• HIRATA TAKEO

• MIYAMOTO MASUO

Abstract

In order to isolate the hypocholesterolemic principle, the neutral ethyl acetatesoluble fraction of the methanol extract of Alismatis Rhizoma was fractionated in parallel with the biological test. Thus new compounds alisol A (1), alisol B (2), alisol A monoacetate (3), alisol B monoacetate (4) and alisol C monoacetate (5) were obtained. The compounds 1, 3, 4 and 5 were shown to be effective in the test with rats.

Journal

• Chemical and Pharmaceutical Bulletin

  Chemical and Pharmaceutical Bulletin 18 (7), 1347-1353, 1970

  The Pharmaceutical Society of Japan

Keywords

• Drug Discovery
• General Chemistry
• General Medicine

Details

• CRID: 1390282679145878912
• NII Article ID: 110003654618
• NII Book ID: AA00602100
• DOI: 10.1248/cpb.18.1347
• COI: 1:CAS:528:DyaE3cXkvF2jtLk%3D
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 5453974
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/18/7/18_7_1347/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1971047643
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed