Studies on Fungicides. XXIV. Reaction of 5-Methoxycarbonylmethylidene-2-thioxo (or oxo)-4-thiazolidones with o-Aminobenzenethiol and Other Thiols

• 長瀬 弘始

抄録

By a novel addition reaction of o-aminobenzenethiol to 5-methoxycarbonylmethylidene-2-thioxo (or oxo)-4-thiazolidones (I) were obtained 5-(3-oxo-2, 3-dihydro-4H-1, 4-benzothiazin-2-yl)-2-thioxo (or oxo)-4-thiazolidones (III). I was also found to reat with thiols to afford 1 : 1 adducts (II and VI) in the presence of a catalytic amount of triethylamine. Thermal cyclization of the adducts (II) to III was observed. The adducts (VI) were proved to dissociate into I and thiols when heated above their melting points or dissolved in acetone or ethanol. Oxidation of III and VI gave the dehydro-compounds (IV and VIII), respectively.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 22 (1), 42-49, 1974

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204176868736
• NII論文ID: 110003632969
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.22.42
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 4833374
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/22/1/22_1_42/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1974081741
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可