Effect of phospholipid on lipid metabolism in experimental fatty liver.

DOI Web Site PubMed

この論文をさがす

抄録

Effect of phospholipid on fatty liver induced by orotic acid, carbon tetrachloride, or ethionine has been studied. Results are summarized as follows : 1. Orotic acid induced a marked accumulation of liver glycerides, and a decreased concentration of liver phospholipid and protein, and of serum beta-lipoprotein. These lesions were restored by administration of phospholipid. 2. In rats given carbon tetrachloride or ethionine, liver lipid accumulation and a decreased concentration of serum beta-lipoprotein were partially restored by administration of phospholipid, but a decreased protein content in the liver was unaffected. These results indicate that administration of phospholipid is effective in counteracting the depression of serum beta-lipoprotein and liver lipid accumulation by orotic acid, carbon tetrachloride, or ethionine. Phospholipid appears to have an important role in normal release of beta-lipoprotein.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ