Spasmolytic substances from Cimicifuga dahurica Maxim.

• 伊藤 基子

• 近藤 嘉和

• 竹本 常松

抄録

The search for spasmolytic principals of Cimicifuga dahurica MAXIM. (Ranunculaceae) with the guidance of the intestinal action resulted in the isolation of two active substances, visamminol and visnagin, in addition to isoferulic acid and norvisnagin. Norvisnagin was first isolated from natural source. Pharmacological estimations using guinea pig jejunum revealed that the spasmolytic actions of visamminol and visnagin were one-third and one-tenth that of papaverine hydrochloride, respectively. Norvisnagin showed inactivity.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 24 (4), 580-583, 1976

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204164061952
• NII論文ID: 110003635017
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.24.580
• COI: 1:CAS:528:DyaE28XktFOisLY%3D
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 949812
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/24/4/24_4_580/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1977059629
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可