Syntheses of chlorpromazine undecahydrododecaborate and nonahydrodecaborate-promising agents for neutron capture therapy of malignant melanoma.
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It has been suggested by dermatologists that boron compounds of chlorpromazine are promising agents for neutron capture therapy of malignant melanoma. The compounds are desired to have a high boron content, good stability, and sufficient solubility in water. To fulfil these requirements, chlorpromazine undecahydrododecaborate and nonahydrodecaborate have been synthesized starting from 2-chloro-10 (3-bromopropyl) phenothiazine and ammonioundecahydrododecaborate or 2-ammoniononahydrodecaborate, respectively.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 24 (4), 778-781, 1976
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679149412224
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- NII論文ID
- 110003635043
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- PubMed
- 949818
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可