Effect of biotin on biochemical changes following isoproterenol-induced myocardial infarction in rats.

• 坪井 俊紀

• 藤谷 武一

• 武野 一子

• 吉田 耕一

• 清水 当尚

抄録

Effect of biotin on biochemical changes following isoproterenol-induced myocardial infarction in rats was investigated. Biotin inhibited an increase of myocardial water content, an elevation of plasma lactate dehydrogenase activity and a decrease of myocardial adenosine triphosphate (ATP) level in isoproterenol-treated rats. Prednisolone enhanced the inhibitory effects of biotin on myocardial water content and plasma lactate dehydrogenase activity, but did not influence on myocardial ATP level. A possible mechanism of the inhibition by biotin is discussed.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 24 (6), 1123-1127, 1976

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204173685120
• NII論文ID: 110003635106
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.24.1123
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 1021277
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/24/6/24_6_1123/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1977079895
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可