Extraction-spectrophotometric determination of berberine in pharmaceutical preparations with 2,6-dichlorophenolindophenol.

• 酒井 忠雄

• 原 逸子

• 坪内 正弘

抄録

A new application of monoacidic dye is reported for the determination of berberine. The method is based on solvent extraction into nitrobenzene of an ion-pair compound formed between 2, 6-dichlorophenolindophenol and berberine. Berberine is determined by measuring absorbance of the extracts over the range of (1-5)×10^-6M (0.408-2.04μg/ml) at 650 nm. The molar absorptivity was 3.8×10⁴l, mol^-1, cm^-1. Continuous variations plots have a maximum at 0.5 mol fraction of DCIP, indicating a 1 : 1 DCIP-berberine ratio.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 25 (9), 2451-2455, 1977

  公益社団法人 日本薬学会

キーワード

• pharmaceuticals

詳細情報

• CRID: 1390001204168255232
• NII論文ID: 110003622746
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.25.2451
• COI: 1:CAS:528:DyaE2sXmtVKmtLg%3D
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/25/9/25_9_2451/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1978106897
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可