Ammonia adducts of chloramphenicol and chloramphenicol palmitate.

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Chloramphenicol and chloramphenicol palmitate were found to form adducts with ammonia. Both ammonia adducts are so unstable at room temperature that ammonia free antibiotics are easily recovered by rapid elimination of ammonia. Particle size was reduced for chloramphenicol palmitate by repeating sorption and subsequent desorption of ammonia.

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