Studies on peptides. LXXVIII. Synthesis of the nonacosapeptide corresponding to the entire amino acid sequence of avian glucagon (duck).

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The nonacosapeptide corresponding to the entire amino acid sequence of duck glucagon was synthesized using methanesulphonic acid as a deprotecting reagent at the final step of the synthesis. Synthetic duck glucagon was obtained in a crystalline form and exhibited the biological activity equivalent to that of porcine glucagon. However, the immunological property of synthetic duck glucagon was found to differ from the mammalian origin.

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