New angiotensin analogues: 8-(L-.ALPHA.-methyl-3,4-dihydroxyphenylalanine)-angiotensin II.

• 荒川 規矩男

• 平田 光輝

• 渡辺 好一郎

• 久我 広

• 服部 英三

抄録

Two analogues of [Ile⁵]-angiotensin II with the substitution of C-terminal phenyl-alanine by L-α-methyl-3, 4-dihydroxyphenylalanine have been synthesized. The agonistic activity in the rat blood pressure was largely diminished, and the antagonist activity to parent angiotensin II was also much weaker than that of [Sar, ¹ Ile⁸]-angiotensin II. Both two analogues did not act as antagonists to norepinephrine.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 27 (4), 1030-1033, 1979

  公益社団法人 日本薬学会

キーワード

• norepinephrine

詳細情報

• CRID: 1390001204172357632
• NII論文ID: 110003662286
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.27.1030
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 476857
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/27/4/27_4_1030/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1980035463
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可