Identification of hydrazine derived from hydralazine in experimental animals.

• 野田 敦子

• 松山 賢治

• 顔 淑恵

• 尾辻 望

• 井口 定男

• 野田 浩司

抄録

The liberation of hydrazine from hydralazine was demonstrated in rabbit urine, in rat plasma and in a rat enzyme system. The identification of hydrazine in rabbit urine was performed by comparison of the gas chromatogram and mass spectrum of its benzalazine derivative with those of an authentic sample. Small amounts of hydrazine extracted from rat plasma and the rat enzyme system were detected by mass fragmentography using ¹⁵N-hydrazine.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 27 (8), 1938-1941, 1979

  公益社団法人 日本薬学会

キーワード

• determination by GC and GC-MS

詳細情報

• CRID: 1390282679149924352
• NII論文ID: 110003623755
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.27.1938
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 540361
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/27/8/27_8_1938/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1980085547
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可