Adsorption of benzothiadiazines by carbon black from aqueous solution, and related phenomena.
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Abstract
The adsorption of benzothiadiazines by carbon black from aqueous solution was investigated in detail. The adsorption isotherms obtained were well described by the Langmuir equation. It was shown that the adsorbability was positively related to the relative diuretic activity. The adsorption was found to be reversible with change of temperature in a perturbation experiment, suggesting a physical adsorption mechanism. The pH of the buffer solution had no clear effect on the adsorption of benzothiadiazines near the neutral pH region. It was shown qualitatively by thin-layer chromatography that the hydrolysis of benzothiadiazines was accelerated by carbon black.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 28 (11), 3426-3430, 1980
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001204161558144
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- NII Article ID
- 110003623856
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed