Biosynthesis of mangiferin in Anemarrhena asphodeloides Bunge. I. The origin of the xanthone nucleus.

• 藤田 正雄

• 井上 隆夫

抄録

Phenylalanine-1-¹⁴C, -2-¹⁴C and -3-¹⁴C, and malonic acid-2-¹⁴C were efficiently incorporated into mangiferin (1) in Anemarrhena asphodeloides. In the case of feeding with phenylalanine-1-¹⁴C, -2-¹⁴C and malonic acid-2-¹⁴C, the radioactivity of 1 was localized in the phloroglucinol ring. Furthermore, cinnamic acid-3-¹⁴C and p-coumaric acid-2-¹⁴C were also incorporated into 1 and isomangiferin (2), but benzoic acid-, p-hydroxybenzoic acid-and protocatechuic acid-(carboxyl-¹⁴C) were essentially not incorporated into 1 or 2. In addition to the above data, doubly labelled p-coumaric acid was incorporated into 1 without change of the T/¹⁴C ratio. These results show that the aglycone of 1 and 2 was biosynthesized from p-coumarate (C₆-C₃) and two malonates (C₄).

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 28 (8), 2476-2481, 1980

  公益社団法人 日本薬学会

キーワード

• malonic acid-2-<SUP>14</SUP>C

詳細情報

• CRID: 1390282679142699904
• NII論文ID: 110003624048
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.28.2476
• COI: 1:CAS:528:DyaL3cXmtFOqtbo%3D
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/28/8/28_8_2476/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1981177692
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可