Synthesis of (23R)-calcidiol lactone (25-hydroxyvitamin D3 26,23-lactone).

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Abstract

(23R)-Calcidiol lactone(25-hydroxyvitamin D3 26, 23-lactone) was synthesized from bisnorcholenic acid. The configuration at C-23 was determined by transformation to 22- and 23-hydroxycholesterols.

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