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The effects of metal compounds on nuclear mitotic cross-over, mitotic gene conversion and reversion were studied in a diploid yeast, Saccharomyces cerevisiae strain D7. All metal compounds used in these experiments had cell killing effects at concentrations of 10-2 to 10-4M. These metal compounds were classified into two groups according to their effects on strain D7. Chromium, arsenic, cadmium, cobalt and nickel compounds induced mitotic cross-over and gene conversion. Lead, mercury and zinc compounds induced mitotic gene conversion at only limited frequencies but the frequency of mitotic cross-over among the convertants was significantly higher than in the control. No increase in reversion frequencies was observed with these compounds.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 30 (8), 3017-3019, 1982
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679141187456
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- NII論文ID
- 110003634710
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- PubMed
- 6754115
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可