Polycystic Kidney Complicated by Cholangiocellular Carcinoma Presenting as Fever of Unknown Origin

DOI 被引用文献1件 参考文献14件
  • Ikeda Nobuhiro
    Department of General Medicine, Juntendo University School of Medicine
  • Naito Toshio
    Department of General Medicine, Juntendo University School of Medicine
  • Isonuma Hiroshi
    Department of General Medicine, Juntendo University School of Medicine
  • Dambara Takashi
    Department of General Medicine, Juntendo University School of Medicine
  • Hayashida Yasuo
    Department of General Medicine, Juntendo University School of Medicine

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We report the case of a 59-year-old man who presented with classical-type fever of unknown origin (FUO) during observation of hypertension and polycystic kidney. The presence of malignancy was suspected based on elevation of tumor marker levels. We examined the patient carefully and attempted diagnostic imaging, but definitive diagnosis was difficult due to the presence of multiple hepatic cysts. Hepatic biopsy detected adenocarcinoma, but identifying whether lesions were primary cholangiocellular carcinoma or metastases was difficult, and we were ultimately unable to diagnose the tumors as cholangiocellular carcinoma until autopsy. Polycystic kidney with hepatic cysts and complicated by cholangiocellular carcinoma is rare, but should be considered among the differential diagnosis for FUO, which itself is frequently encountered.

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