Severe Retinopathy in Fulminant Juvenile Dermatomyositis

• Gushiken Naoki

  Department of Ophthalmology Okinawa Chubu Hospital

• Yoshimura Hiroshi

  Department of Pediatrics, Okinawa Chubu Hospital

• Toyoura Makiko

  Department of Pediatrics, Okinawa Chubu Hospital

• Fujiwara Naoki

  Department of Pediatrics, Okinawa Chubu Hospital

• Tokuda Yasuharu

  Clinical Practice Evaluation and Research Center, St. Luke's Life Science Institute

抄録

We present a case of juvenile type dermatomyositis and severe retinopathy. A 10-year-old girl presented with progressive weakness of proximal muscles, generalized rash, including heliotrope-type eyelid erythema, and bilateral visual disturbance. Laboratory data showed a markedly elevated serum creatine kinase and electromyography revealed a myogenic pathology. Funduscopic examination showed numerous cotton wool spots and macular edema. She developed massive rhabdomyolysis, generalized skin lesions, systemic edema, renal failure, and respiratory failure. After she received steroid pulse therapy, plasma exchange, and high-dose immunoglobulin, her general condition and visual symptoms improved. She remained well when we followed up her condition 5 years after the discharge.

収録刊行物

• Ｇｅｎｅｒａｌ　Ｍｅｄｉｃｉｎｅ

  Ｇｅｎｅｒａｌ　Ｍｅｄｉｃｉｎｅ 8 (1), 25-28, 2007

  一般社団法人 日本プライマリ・ケア連合学会

キーワード

• Dermatomyositis
• Retinopathy
• Retinal Vasculitis
• Rhabdomyolysis
• Plasma Exchange

詳細情報

• CRID: 1390001205189255168
• NII論文ID: 130003822175
• NII論文ID: 10019971904
• NII書誌ID: AA11571086
• DOI: 10.14442/general2000.8.25
• ISSN: 18836011
• ISSN: 13460072
• Web Site: https://search.jamas.or.jp/link/ui/2008171564
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可