突発性難聴の病理

書誌事項

タイトル別名
  • Pathology of sudden deafness

抄録

The causes of sudden deafness are discussed based on our own temporal bone studies and on those reported in the literature, focusing specifically on the pathology of the tectorial membrane. Changes in the tectorial membrane in patients with sudden deafness are similar to those observed in patients with known viral diseases, such as measles and mumps. It is noteworthy that the absence of interdental cells is a common finding.<br>Inoculation of the guinea pig cochlea with herpes simplex virus I results in similar pathological changes of the tectorial membrane. Immunofluorescence studies demonstrated the presence of viral antigen in the tectorial membrane as well as in the interdental cells.<br>One of our own cases, published in 1976, was reviewed. The patient developed bilateral sudden deafness immediately after undergoing severe psychological stress, which appeared to trigger the condition.<br>While the tectorial membrane of both sides exhibited different features, the findings were suggestive of viral infection. The interdental cells were absent.<br>The most likely etiology of sudden deafness in patients who do not show recovery of hearing is probably viral infection. It is conceivable that a latent viral infection is reactivated in these cases.

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詳細情報

  • CRID
    1390282679819305344
  • NII論文ID
    130003863783
  • DOI
    10.4295/audiology.49.777
  • ISSN
    18837301
    03038106
    http://id.crossref.org/issn/03038106
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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