髄液鼻漏に対する内視鏡下鼻内的閉鎖術の経験

  • 石田 春彦
    神戸大学大学院医学系研究科器官治療医学講座 耳鼻咽喉・頭頸部外科学分野
  • 鳥山 満由
    神戸大学大学院医学系研究科器官治療医学講座 耳鼻咽喉・頭頸部外科学分野
  • 木村 真実
    神戸大学大学院医学系研究科器官治療医学講座 耳鼻咽喉・頭頸部外科学分野
  • 井上 博之
    神戸大学大学院医学系研究科器官治療医学講座 耳鼻咽喉・頭頸部外科学分野
  • 丹生 健一
    神戸大学大学院医学系研究科器官治療医学講座 耳鼻咽喉・頭頸部外科学分野

書誌事項

タイトル別名
  • ENDOSCOPIC ENDONASAL REPAIR OF CSF LEAKS TO THE SINONASAL TRACT

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Patients with cerebrospinal fluid (CSF) rhinorrhea may develop life-threatening complications such as meningitis, pneumocephalus, and brain abscesses. Closure of the fistula is required to prevent these complications. A variety of techniques, including conservative management and surgery, have been reported for the treatment of CSF rhinorrhea. Recently, endoscopic endonasal closure of the fistula has been used with good results.<br>Three patients underwent endoscopic endonasal repair procedures at Kobe University Hospital for the treatment of CSF rhinorrhea fistulas connecting the anterior skull base and the sinonasal tract. Two patients developed CSF leaks after undergoing neurosurgical procedures involving the anterior skull base. The specific sites of the leaks in these two patients were the ethmoid sinus and the sphenoid sinus. The third patient developed idiopathic CSF rhinorrhea of the cribriform plate. In all three patients, autologous grafts of their abdominal fat with fascia or the mucosal flap of the middle turbinate were used to repair the fistulas. The idiopathic CSF leak was successfully closed. However, recurrences developed in the two patients who had undergone previous neurosurgical treatment. In the patient who developed a CSF leak from the sphenoid sinus, the fistula could not visualized because of scar tissue. In the patient who developed a CSF leak from the ethmoid sinus, multiple bone defects and fistulas were found. These difficult surgical conditions are considered to be the main reasons for the unsuccessful outcome.

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