透析患者における副甲状腺腫切除術の心臓に及ぼす影響

DOI

書誌事項

タイトル別名
  • The effects of parathyroidectomy on the heart in dialysis patients.

抄録

In order to examine the influences of secondary hyperparathyroidism on the heart in dialysis patients, we conducted a study to observe changes in cardiac function and morphology at one year following parathyroidectomy (PTX).<br>The subjects were 14 PTX cases (3 cases on CAPD and 11 cases on hemodialysis) and 14 sex-, age-, and duration-matched cases (4 cases on CAPD and 10 cases on hemodialysis). Using M-mode echocardiography we studied the following parameters before and one year after PTX in PTX cases and for a one year period in the control cases: interventricular septal thickness (IVS), left ventricular posterior wall thickness (PW), left ventricular end-diastolic dimension (LVDd), left ventricular end-systolic dimension (LVDs), left ventricular mass index (LVMI), cardiac index (CI), left ventricular ejection fraction (EF), mean velocity of circumferential fiber shortening (mVcf), and relative wall thickness (RWT). At the same time, we monitored heart rate (HR), systolic blood pressure (sBP), diastolic blood pressure (dBP), cardiothoracic ratio (CTR), c-terminal parathyroid hormone (c-PTH), calcium (Ca), phosphate (P) and hematocrit (Ht).<br>None of those parameters changed significantly in the control cases. On the other hand, IVS, PW, LVDd, LVMI, and CI were reduced without changes in EF, mVcf, and RWT at one year following PTX.<br>In patients with secondary hyperparathyroidism, myocardial wall thickness and left ventricular dimension were reduced during the one-year period after parathyroidectomy. The present data show that eccentric myocardial hypertrophy is a consequence of excessive parathyroid hormone.

収録刊行物

キーワード

詳細情報 詳細情報について

  • CRID
    1390001204677034496
  • NII論文ID
    130003874628
  • DOI
    10.4009/jsdt.27.1133
  • ISSN
    1883082X
    13403451
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

問題の指摘

ページトップへ