ウマの膵臓の膵島-腺房門脈系

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タイトル別名
  • Insulo-Acinar Portal System in the Horse Pancreas
  • ウマ ノ スイゾウ ノ スイトウ-セン ボウモン ミャクケイ エイブン

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抄録

The horse pancreas was arterially injected with India ink. After fixation slices were made by hand and cleared in methyl salicylate for microscopic observation.<br>1. Each islet receives an end branch of the intralobular artery. This artery does not directly supply the acinar tissue, except for issuing rare branches breaking up in smaller, islet-free regions of the pancreas.<br>2. The arteriole reaches a central point of the islet and abruptly breaks up into swollen capillaries which extend to the periphery of the islet.<br>3. Thin efferent vessels radiate to communicate, at a certain distance from the islet margin, with the capillary net of the acinar tissue.<br>4. The horse exocrine pancreas thus receives its blood supply almost entirely, if not exclusively, through the islet. The efferent vessels may functionally be called “portal” though they are capillaries in structure. They convey to the exocrine tissue islet hormones which have recently been learned from our parallel study to be secretagogues to the exocrine pancreas.<br>5. The vascular route leading the blood from the center to the periphery of the islet in the horse seems purposeful, because glucagon issued from the A cells which are gathered in the islet center in this animal can exert its function as an insulin releaser upon the B cells downstream. In the rabbit which has central B cells and peripheral A cells the vessels are designed to lead blood from the periphery to the center.

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