カドミウム曝露の腎臓への影響の指標: N-acetyl-β-D-glucosaminidaseを中心に

• 川田 智之

  Department of Public Health, Gunma University School of Medicine

書誌事項

タイトル別名

• Indicators of Renal Effects of Exposure to Cadmium: N-Acetyl-β-D-Glucosaminidase and Others
• Indicators of Renal Effects of Exposure

抄録

The renal effects of cadmium (Cd) have been studied in industrial workers exposed to Cd and inhabitants of Cd-polluted districts, as the kidney is a critical organ in exposure to Cd. Several biological indicators of Cd have been proposed including N-acetyl-β-D-glucosaminidase (NAG) and β₂-microglobulin (BMG) in urine for the detection of early renal effects. The average concentrations of Cd in urine samples were over 10 μg/g·creatinine in classic researches. Even in the industrial field, this exposure level is now hardly observed in Japan and western countries. The situation is the same with inhabitants in general living in a Cd-polluted district. From the viewpoint of consistency of the association, the relationship between Cd and NAG has become fairly definite. Stability in the pH change, simplicity, low cost and the reliability of measurements were also satisfactory. NAG is one of the recommended tools for detecting minimum renal effects under 10 μg/g·creatinine of Cd.

収録刊行物

• 産業衛生学雑誌

  産業衛生学雑誌 37 (2), 69-73,A30, 1995

  公益社団法人 日本産業衛生学会

キーワード

• Cadmium poisoning
• Urinary cadmium
• N-acetyl-β-D-glucosaminidase
• β₂-microglobulin
• Renal effect

詳細情報

• CRID: 1390282679676737920
• NII論文ID: 130003888901
• NII論文ID: 10005662222
• NII書誌ID: AN10467364
• DOI: 10.1539/sangyoeisei.37.2_69
• ISSN: 1349533X
• ISSN: 13410725
• NDL書誌ID: 3645540
• PubMed: 7749995
• Web Site: http://id.ndl.go.jp/bib/3645540
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I3645540
• Web Site: https://www.jstage.jst.go.jp/article/joh1995/37/2/37_2_69/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1996041930
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  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
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