擦過細胞診で診断し得た胎盤ｃｈｏｒｉｏａｎｇｉｏｍａの１例

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  • A case of placental chorioangioma diagnosed by scraping cytology.

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Chorioangioma is the most common benign placental tumor, occurring in approximately 1 percent. Large tumors are but are more commonly associated with maternal and neonatal complications. We report a case which histologic type could be diagnosed by means of scraping cytology after delivery.<BR>A 27 year old primipara delivered a female weighing 2, 280 gr. spontaneously at 39 gestational weeks. Her prenatal course was uneventful. Placental weight was 1, 158 gr. as a whole. A large 15×10×8cm-sized mass was attached to the fetal membrane on the maternal surface and another three, 4×4×3, 3×2×2, 2×2×2 cm sized masses were found in the center of the placenta. Scraping cytology showed clusters of cells with oval to spindle shaped nuclei against bloody but clean background. Some clusters had a characteristic feature of blood filled capillary-like structure. These cells were considered to be originated from placental chorioangioma.<BR>Histologically, masses were typical chorioangioma and immunohistochemically, factor VIII was positive in the tumor cells by PAP method. The result confirms that the origin of chorioangioma is the fetal vessels.<BR>No severe maternal and fetal complication was observed except for slight degree of IUGR, though the size of the tumor was very large.

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