書誌事項
- タイトル別名
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- Aspiration cytology of Epithelial-myoepithelial carcinoma of the Salivary gland: A double-immunohistochemical study for keratin and alpha-smooth muscle actin.
- A double-immunohistochemical study for keratin and alpha-smooth muscle actin
- ケラチンと平滑筋アクチンの二重免疫染色による検討
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Objective: We clarified the typical cytological features and diversity of epithelial-myoepithelial carcinoma of the salivary gland.<BR>Study Design: We compared preoperative fine-needle aspiration cytology and histological specimens from 4 cases of epithelial-myoepithelial carcinoma, conducting double immunostaining for keratin (KL-1) and alpha-smooth muscle actin (SMA). We also conducted immunohistochemical studies using epithelial and myoepithelial markers.<BR>Results: Epithelial cell clusters having dispersed cells with naked nuclei in the background were characteristic of typical cellular tumors without basement membrane thickening. Mucous globules reminiscent of adenoid cystic carcinoma were rarely seen. SMA clearly marked myoepithelial components at the periphery of cell clusters and background in cytological specimens, as did KL-1 for epithelial components at the center of cell clusters.<BR>Conclusion: Although cytological tumor features were typical, cytology alone would be insufficient for a definitive diagnosis. Double immunostaining was useful in distinguishing epithelial and myoepithelial components in cytological specimens.
収録刊行物
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- 日本臨床細胞学会雑誌
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日本臨床細胞学会雑誌 41 (4), 251-259, 2002
公益社団法人 日本臨床細胞学会
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詳細情報 詳細情報について
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- CRID
- 1390001204694033024
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- NII論文ID
- 130003926738
- 110001231314
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- NII書誌ID
- AN00198721
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- ISSN
- 18827233
- 03871193
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可