Cytotoxic Quassinoids and Tirucallane-Type Triterpenes from the Woods of Eurycoma longifolia.

• 糸川 秀治

• 岸 悦子

• 森田 博史

• 竹谷 孝一

抄録

New cytostatic quassinoids, 6α-hydroxyeurycomalactone (1), longilactone (2) and 14, 15β-dihydroxyklaineanone (3) were isolated from the woods of Eurycoma longifolia (Simaroubaceae) with three cytotoxic quassinoids, 11-dehydroklaineanone (4), eurycomalactone (5) and 5, 6-dehydroeurycomalactone (6), and with seven cytotoxic tirucallane-type triterpenes, niloticin (7), dihydroniloticin (8), piscidinol A (9), bourjotinolone A (10), 3-episapelin A (11), melianone (12) and hispidone (13). All of them showed potent cytotoxic activity against P388 and KB cells.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 40 (4), 1053-1055, 1992

  公益社団法人 日本薬学会

キーワード

• quassinoid
• triterpene
• cytotoxic activity
• Eurycoma longifolia
• Simaroubaceae

詳細情報

• CRID: 1390001204159275776
• NII論文ID: 130003945926
• DOI: 10.1248/cpb.40.1053
• COI: 1:CAS:528:DyaK38XkvVKktrc%3D
• ISSN: 13475223
• ISSN: 00092363
• ISSN: http://id.crossref.org/issn/00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/40/4/40_4_1053/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可