Investigation of the Microprecipitation of Folic Acid from Slightly Acidic Injection Solutions Using Dynamic Light Scattering.

• KEKI Sandor

• SIPOS Tamas

• DEAK Gyorgy

• MEZEY Geza

• ZSUGA Miklos

抄録

Microprecipitation of folic acid was monitored by the dynamic light scattering (DLS) method. The pH was changed by CO₂ absorption and addition of HCl. The folic acid solutions were examined over the pH range 8.5-4.0. Over the pH range 5.4-6.0, microprecipitation was observed and at pH ≤5.2 crude precipitation of folic acid occurred. The dependence of the effective diameter on the pH over the pH range 5.4-6.0 is also reported.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 46 (8), 1333-1334, 1998

  公益社団法人 日本薬学会

キーワード

• dynamic light scattering
• folic acid injection
• folic acid precipitation
• microprecipitation

詳細情報

• CRID: 1390282679138520448
• NII論文ID: 130003947651
• DOI: 10.1248/cpb.46.1333
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/46/8/46_8_1333/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可