辺縁性歯周炎の免疫病理学的研究　Ｖ‐３　　膜透析法によるＡｃｔｉｎｏｍｙｃｅｓ抗原特異的免疫担当細胞の検出

• 竹内 宏

  岐阜歯科大学口腔病理学講座

• 金久 純也

  岐阜歯科大学口腔病理学講座

• 堀 泰典

  岐阜歯科大学口腔病理学講座

• 上田 雅俊

  大阪歯科大学歯周病学講座

• 河野 忠雄

  大阪歯科大学細菌学講座

• 谷 明

  大阪歯科大学細菌学講座

• 佐川 寛典

  大阪歯科大学細菌学講座

書誌事項

タイトル別名

• Immunopathological study of periodontal disease
• 第5報 その (3) 膜透析法によるActinomyces抗原特異的免疫担当細胞の検出

抄録

To detect the subpopulation or subset of immunecompetent cells which specifically react with oral bacterial antigens, it is most significant to clarify the correlation of immune reaction to periodontal diseases. But the method is very difficult because of lack of the precise technique to demonstrate cells which react with the antigens.<BR>In this study, the above problem was solved by a direct fluorescent antigen technique utilizing the membrane dialysis method. The FITC conjugation of a soluble antigen obtained from the mixture of Actinomyces naeslundii and A. viscosus showed an affinity with immunecompetent cells as small lymphocytes or plasma cells and a part of the inflammatory exudate in the inflamed human gingivae. The method was convenient and the results were high specific. Consequently, it was concluded that this membrane dialysis method was usefull for prospective serious immunopathological studies of periodontal diseases.

収録刊行物

• 歯科基礎医学会雑誌

  歯科基礎医学会雑誌 24 (3), 746-751, 1982

  歯科基礎医学会

キーワード

• fluorescence antigen technique
• specific immunecompetent cell
• Actinomyces antigen
• periodontal disease

詳細情報

• CRID: 1390282679659094272
• NII論文ID: 130004001123
• DOI: 10.2330/joralbiosci1965.24.746
• ISSN: 03850137
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可