Ｌｉｎｅａｒ　ＩｇＡ　Ｂｕｌｌｏｕｓ　Ｄｅｒｍａｔｏｓｉｓの２例

• 廣田 さち子

  奈良県立医科大学皮膚科学教室

• 福本 隆也

  奈良県立医科大学皮膚科学教室

• 白井 利彦

  奈良県立医科大学皮膚科学教室

書誌事項

タイトル別名

• Two Cases of Linear IgA Bullous Dermatosis.

抄録

Two cases of linear IgA bullous dermatosis are reported. Patient 1, a 38-year-old woman presented with generalized pruritic vesicles. She had episodes of recurrent eruptions for 10 years before a biopsy confirmed the diagnosis. Patient 2, a 84-year-old man presented with a month history of tense bullous eruptions on abdomen to thighs. Histopathologically, in both of two cases, the skin lesions showed the subepidermal blister with eosinophils and neutrophils. Direct immunofluoresence of the patient 1 showed linear deposition of IgA and C3 at the basement membrane zone (BMZ), of the patient 2 showed IgA at BMZ. Both of patients were negative for circurating anti-BMZ IgA antibody. However they became positive when the salt-split skin method was applied. She was treated with DDS 50mg daily and has been off drug for 3 years without relapse. He was successfully treated with azelastine 2mg daily for 7 days and a topical corticosteroid. She has HLA typing A24 B7 BW54 CW1 CW7 DR1 DR4 DRW53 DQW1 DQW4.

収録刊行物

• 皮膚

  皮膚 35 (4), 483-487, 1993

  日本皮膚科学会大阪地方会

キーワード

• inear IgA bullous dermatosis
• DDS
• azelastine
• HLA
• salt-split skin method

詳細情報

• CRID: 1390001204799729536
• NII論文ID: 130004045532
• NII論文ID: 80007225555
• DOI: 10.11340/skinresearch1959.35.483
• ISSN: 1884541X
• ISSN: 00181390
• Web Site: https://search.jamas.or.jp/link/ui/1994033028
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可