Immunocytochemical Studies of Corticotropin Releasing Factor-like Immunoreactive Innervation of Atrial Natriuretic Peptide Neurons in the Rat Diencephalon

• SANO Hiroaki

  <I>Department of Anatomy, Showa University School of Medicine</I>

• HAYASHI Takaki

  <I>Department of Anatomy, Showa University School of Medicine</I>

• SHIODA Seiji

  <I>Department of Anatomy, Showa University School of Medicine</I>

• NAKAI Yasumitsu

  <I>Department of Anatomy, Showa University School of Medicine</I>

抄録

Synaptic inputs of corticotropin-releasing factor (CRF) -like Immunoreactive axon terminals to neurons containing atrial natriuretic peptide (ANP) in the anteroventral third ventricle (AV3V) region of the rat diencephalon were examined ultrastructurally by a pre-embedding double immunostaining technique combining the silver-gold intensified peroxidase-antiperoxidase complex-3, 3'-diaminobenzidine (SGI-PAP-DAB) method for ANP with the nonintensified PAP-DAB method for CRF. CRF-like Immunoreactive axon terminals were found to make asymmetrical or symmetrical synaptic contacts with ANP-like Immunoreactive nerve cell bodies and processes in the AV3V region. These findings suggest that CRF-containing neurons may regulate the secretory activity, or other functions, or both, of ANP-containing neurons through synapses in the AV3V region of the rat diencephalon.

収録刊行物

• Ｔｈｅ　Ｓｈｏｗａ　Ｕｎｉｖｅｒｓｉｔｙ　Ｊｏｕｒｎａｌ　ｏｆ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅｓ

  Ｔｈｅ　Ｓｈｏｗａ　Ｕｎｉｖｅｒｓｉｔｙ　Ｊｏｕｒｎａｌ　ｏｆ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅｓ 4 (2), 161-168, 1992

  昭和大学学士会

キーワード

• synapse
• CRF-containing terminal
• ANP-containing neuron
• rat AV3V
• immunoelectron microscopy

詳細情報

• CRID: 1390282679348939392
• NII論文ID: 130004070312
• DOI: 10.15369/sujms1989.4.161
• ISSN: 21850968
• ISSN: 09156380
• Web Site: https://www.jstage.jst.go.jp/article/sujms1989/4/2/4_2_161/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可