歯科治療時の交感神経活動に対する自律訓練法の抑制効果について(血中グルコース,遊離脂肪酸を指標として) (第2報)

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  • The suppressive effects of autogenic training to sympathetic nerve activity under dental procedure(Indicating of plasma glucose and free fatty acid). (2nd report).

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To determine the inhibitory effect of autogenic training (AT) to control accelerated smpathetic nerve activity at the time of dental therapies, a comparative review was made studying the effects of beta-blocker by measuring the serum level of glucose and free fatty acids (FFA) as indices. As a dental therapeutic model, physiological saline solution was injected into the oral cavity.<BR>The subjects were 35 volunteer male students in Nihon University School of Dentistry.<BR>These volunteers were divided into the following groups; Group 1: 15 subjects trained for AT up to the second formula. Group 2: 8 subjects pre-treated with 10mg of a beta-blocker indenolol hydrochloride. Group 3: 12 control group subjects.<BR>Method<BR>AT was performed once a week, and training was continued until the subject became conscious of the heavy warm feeling of a hand or foot. Training was carried out 4 to 6 times. Group 2 was orally administered of 10mg indenolol hydrochloride, a first generation betablocker, one hour before injection into the oral cavity. Blood was collected before and after injection.<BR>Result<BR>Before and after injection, the glucose level showed a lower value in Group 1 compared with that of Groups 2 and 3. The FFA level showed a low level before and after injection in Group 1, followed by Group 2 and 3. Significantly low value was observed in Group 1 compared to Group 3.<BR>As mentioned above, for the accelerated sympathetic nerve activity at the time of dental treatment, training up to the second formula has been suggested to be as effective as the administration of 10mg indenolol hydrochloride.

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