小児神経筋疾患における骨格筋の超音波検査(筋エコー)の検討

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タイトル別名
  • Static B-scan ultrasound imaging in the diagnosis of neuromuscular diseases in children.

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The static B-scan ultrasound imaging of the muscle, an atraumatic and noninvasive technique, was studied on 23 patients (7 children with progressive muscular dystrophy, 2 with congenital muscular dystrophy, 2 with spinal muscular atrophy, 1 with infantile neuroaxonal dystrophy, and 11 with hypotonia of probable muscular origin) and 12 control children.<BR>Transverse and longitudinal ultrasound images of deltoid, biceps, gastrocnemius, and quadriceps muscles were obtained. The intensity of the echo reflected from the muscle was classified into five grades; from 0 (normal) to 4. Grade 1 siginified a slight increase in the muscle echo while bone and fascia echos were distinct, and grade 4 showed a markedly strong muscle echo and a complete loss of bone and fascia echos.<BR>A diagnostic muscle biopsy was performed on 8 of 11 children with hypotonia of probable muscular origin; 5 were found to have the Grade 1 change including a considarable variation in the fiber size and the sarcoplasmic hyperactivity, without significant abnormality of the intramuscular structures as demonstrated by NADH stain. This atraumatic procedure was able to detect a mild change in the muscle.<BR>Ultrasound scanning was very useful for selecting floppy infants for the muscle biopsy. Moreover, this invasive technique was of value in the follow-up for long time period.

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  • 脳と発達

    脳と発達 19 (3), 204-209, 1987

    THE JAPANESE SOCIETY OF CHILD NEUROLOGY

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