紫外線防御の皮膚科学的意義

• 上出 良一

  東京慈恵会医科大学皮膚科

書誌事項

タイトル別名

• Dermatological Significance of the Protection from Ultraviolet Rays.

抄録

Ultraviolet ray is one of the strongest environmental factors which tremendously damages the structure and function of the skin. Acute cutaneous injury caused by UVirradiation includes sunburn and suntan. Chronic UV damage induces photoaging, such as solar lentigo, actinic elastosis, and benign and malignant tumors after a long latent period. The triggering events are direct DNA damage caused by UVB irradiation and the generation of reactive oxygen species initiated by UVA-induced excitation of natural photosensitizers located inside or outside of the cells. As the consequence, cutaneous inflammation, structural modification of the cell, mutation of genes, induction of cancers, inhibition of cutanecous immune reactions, and photosensitive disorders may occur. In this review, clinical symptoms and the mechanisms of harmful effect of UV irradiation, and a strategy to prevent such deleterious effects of UV are discussed.

収録刊行物

• 日本化粧品技術者会誌

  日本化粧品技術者会誌 30 (3), 265-272, 1996

  日本化粧品技術者会

詳細情報

• CRID: 1390001204500946688
• NII論文ID: 130004188726
• DOI: 10.5107/sccj.30.265
• ISSN: 18844146
• ISSN: 03875253
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可