ＡＤＦ／ＴＲＸの産生に及ぼす植物抽出物の影響

• 田中 弘

  株式会社ナリス化粧品研究開発部

• 船坂 陽子

  神戸大学医学部皮膚科学教室

• 市橋 正光

  神戸大学医学部皮膚科学教室

書誌事項

タイトル別名

• The Effect of Plant Extracts on Production of Adult T Cell Leukemia-Derived Factor/Tioredoxin(ADF/TRX).

抄録

With the aim to recognize the materials which increase the tyrosinase activity of melanocytes in the conditioned medium of keratinocytes after UV-B irradiation, we studied the stimulatory effects of conditioned media using ADF/TRX and α-MSH (melanocyte stimulating hormone) antibodies. As a result of the studies, all tyrosinase activities of melanocyte in the conditioned media with ADF/TRX and/or α-MSH antibodies were suppressed efficiently as compared to the medium without the antibodies. As melanin amount is up-regulated by UV-B irradiation that causes skin pigmentation, we searched for a way to suppress the amount of ADF/TRX produced during UV-B irradiation. We found the ingredients that effectively suppress the amount of ADF/TRX, as follows: dl-α-tocopherol, Psidium guajava leaf extract, Thea sinensis L. extract and Helianthus annuus L. seed extract.

収録刊行物

• 日本化粧品技術者会誌

  日本化粧品技術者会誌 34 (4), 395-400, 2000

  日本化粧品技術者会

キーワード

• Adult T Cell Leukemia-Derived Factor/Tioredoxin (ADF/TRX)
• tyrosinase activity
• keratinocyte
• melanocyte
• skin pigmentation
• UV-B irradiation
• conditioned medium
• Western blotting
• <i>dl</i>-α-tocopherol
• <i>Psidium guajava</i> leaf extract
• <i>Thea sinensis</i> L. extract
• <i>Helianthus annuus</i> L. seed extract

詳細情報

• CRID: 1390001204501532544
• NII論文ID: 130004188805
• DOI: 10.5107/sccj.34.395
• ISSN: 18844146
• ISSN: 03875253
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可