伝染性単核症様症候群の２例　腹腔鏡所見および生検肝組織像について

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  • Two cases of infectious mononucleosis-like syndrome with special reference to laparoscopic findings and liver biopsies.

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We report the laparoscopic findings and liver biopsies of two cases of Infectious Mononucleosis-like syndrome. Case 1. A 20-year-old male. He complained of fever and sore throat. Swelling of lymph nodes of his whole body and hepatomeagly were noted. His laboratory data showed that atypical lymphocytosis, positive Paul-Bunnell test, GOT 105 IU/L, GPT 114 IU/L, and LDH 1, 024 IU/L. Case 2. A 32-year-old male. He complained of fever and swelling of cervical lymph nodes. His laboratory data showed atypical lymphocytosis, GOT 103 IU/L, GPT 129 IU/ L and LDH 1, 101 IU/L. Laparoscopic findings of both cases revealed the following. The spleen was enlarged prominently. The liver was slightly enlarged and its surface was smooth. A close-up view showed that white markings were increasing. These are thought to be compatible with the whitish marking of portal areas after ICG infusion. In Case 1, it was possible to observe swelling of mesenteric lymph nodes at laparoscopy. Liver biopsies of both cases revealed moderate small round cell infiltration in the portal areas and along the sinusoids. Cellular infiltration of the Glisson's sheath was severe. Round cell infiltration of the sinusoids was striking. There was almost no fibrosis.

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