骨髄線維症患者にみられた下顎骨骨髄炎の1例

DOI
  • 佐藤 健彦
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University
  • 村西 京一郎
    Department of Oral Surgery, Hokuto Hospital
  • 北川 栄二
    Department of Oral Surgery, Hokuto Hospital
  • 北川 善政
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University

書誌事項

タイトル別名
  • A case of mandibular osteomyelitis in a patient with myelofibrosis

この論文をさがす

抄録

Myelofibrosis is characterized by bone marrow replacement with fibrous tissues, splenomegaly, leukoerythroblastosis and extraosseous hematopoiesis. The cause is unknown but is speculated to be a hyperplastic condition resulting in fibrotic transformation of fibroblasts reacting to a cytokine excreted within the bone marrows.<BR>We herein report a case of osteomyelitis of the mandible in a patient with myelofibrosis. A 55-year-old male patient was referred to our department with chief complaint of spontaneous severed pain and contact pain in the left lower molar region. Ulceration with circumscribed redness and bone exposure were identified at the left lower gingivobuccal fold and swelling was also identified in the left submandibular region, and paresthesia was identified at the left V3 region, which lead to the diagnosis of osteomyelitis. Extraction of unstable teeth was then performed after improvement of the patient's general physical condition. But during the course of hospitalization, the patient developed pneumonia refractory to antibiotic therapy. Because of the possibility of transformation of myelofibrosis to acute myelogenous leukemia (AML), the patient was transferred to another hospital for further examination. He developed severe fungal infection which was successfully treated. He underwent surgery for mandibular osteomyelitis when his general physical condition was improved and stable. No recurrence was confirmed after the treatment but the patient died of cerebral hemorrhage of unknown etiology.

収録刊行物

  • 有病者歯科医療

    有病者歯科医療 16 (3), 137-141, 2007

    一般社団法人 日本有病者歯科医療学会

詳細情報 詳細情報について

問題の指摘

ページトップへ