塩化リゾチーム軟膏（リフラップ｀Ｒ´軟膏）の配合変化　（第２報）

• 西城 一翼

  札幌医科大学附属病院薬剤部

• 深澤 一也

  日立化成工業株式会社山崎工場

• 荒谷 典子

  札幌医科大学附属病院薬剤部

• 藤森 美千子

  札幌医科大学附属病院薬剤部

• 佐藤 浩之

  日立化成工業株式会社山崎工場

• 向尾 正昭

  日立化成工業株式会社山崎工場

• 板谷 幸一

  札幌医科大学附属病院薬剤部

書誌事項

タイトル別名

• Compatibility of lysozyme chloride ointment (Reflap ointment). II.

抄録

Compatibility tests of lysozyme chloride ointment (Reflap^® Ointment) with eleven anti-microbial agents and four disinfectants were carried out. Reflap^® ointment was mixed with other ointments and creams in equal weight. A day's dose of anti-microbial injections and 5 ml disinfectant solutions were, respectively, mixed with 30g Reflap^® ointment. The mixtures in polyethylene airtight vessels were stored at room temperature for two months. Changes of appearance (e. g., color, odor and bleeding), pH level and lysozyme activity were studied.<BR>It was found that the significant reductions of lysozyme activity immediately occured in the cases of the mixture with Chloromycetin^® ointment or Isodime^® gel. The lysozyme activity were reduced with time in the cases of the mixture with Terra-Cortril^® ointment, Fucidin leo^® ointment and Lilacillin^® injection. No changes were observed in any of the other mixtures.

収録刊行物

• 病院薬学

  病院薬学 15 (4), 305-309, 1989

  一般社団法人 日本医療薬学会

キーワード

• compatibility
• Reflap<SUP>®</SUP> ointment
• anti-microbial agents
• disinfectants
• color
• odor
• bleeding
• pH
• lysozyme activity

詳細情報

• CRID: 1390001204776594560
• NII論文ID: 130004299094
• DOI: 10.5649/jjphcs1975.15.305
• ISSN: 21859477
• ISSN: 03899098
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可