フルフェナム酸アルミニウムに起因したと思われる出血性大腸炎の１例

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  • A case of hemorrhagic colitis associated with fulfenamic acid aluminium.

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A 74-year-old female patient had taken 250mg of fulfenamic acid aluminium (FFAA) three times a day for gonarhrisis and two weeks later, abdominal pain, diarrhea bloody stool were obserbed. And she was admitted to our hospital.<br>A barium enema examination showed many diverticles in the descending colon. On the colonoscopic examination performed at the time of admission, edema and reddish mucosa with hemorrhage in the descending colon were noticed. Stool cultures were negative for bacterial and fungal pathogens. FFAA was discontinued and her symptoms disappeared. Lymphocyte stimulation test for FFAA was negative.<br>Three years before, she had had the same symptoms, when she had taken 250mg of FFAA three times a day for 3 months. Discontinuation of taking the FFAA resulted in the disappearance of the symptoms. A tentative diagnosis of hemorrhagic colitis associated with FFAA was made. So far, hemorrhagic colitis associated with FFAA has been reported in three cases including the present one until the year 1990. We discussed our case, compared with 15 cases of hemorrhagic colitis associated with mefenamic acid.

収録刊行物

  • 医療

    医療 47 (12), 999-1003, 1993

    一般社団法人 国立医療学会

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