髄液中のインターロイキン６および８が高値を示し，ＭＲＩで大脳脚に病変を認めたマイコプラズマ髄膜脳炎の１例

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  • A case of acute meningoencephalitis due to Mycoplasma pneumoniae with elevation of interleukin 6 and 8 in cerebrospinal fluid and with lesions of crus cerebri on MRI.
  • ズイエキ チュウ ノ インターロイキン 6 オヨビ 8 ガ タカネ オ シメシ,MRI デ ダイノウ キャク ニ ビョウヘン オ ミトメタ マイコプラズマ ズイマク ノウエン ノ 1レイ

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A 9-year-old boy with Mycoplasma pneumoniae (M, pneumoniae) -related meningoencephalitis is described. Nine days after of a cold, he had a fever, headache and vomitting. Two days later, he was admitted to our hospital with gait disturbance and somnolence. Serum and cerebrospinal fluid (CSF) antibody titers to M, pneumoniae were elevated. The interleukin-6 (IL-6) and Intereukin-8 (IL-8) levels of CSF were high, but tumor necrosis factor- a (TNF-α), interleukin-1 a (IL-1α) and intereukin-1β<br>(IL-1β) levels were not detectable. Serum levels of all cytokines studied were under detection limits. Myelin basic protein (MBP) titer in CSF was high. T2-weighted image of MRI disclosed high signal intensity in crus cerebri, serum anti-galactocerebroside C antibody (anti-GC antibody) were examined 3 times. Those levels were not high but declined day by day. So this case might be a mild type of acute disseminated encephalomyelitis (ADEM).

収録刊行物

  • 医療

    医療 55 (1), 42-45, 2001

    一般社団法人 国立医療学会

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